Osteoarthritis

By Gennaro Polverino, M.D.
Family Medicine Physician

Osteoarthritis (OA) is a common type of noninflammatory arthritis. OA is also sometimes referred to as “wear and tear” arthritis or incorrectly as degenerative joint disease (DJD.) According to Harrison’s Principles of Internal Medicine 15th ed. by Braunwald, et. al., OA in the elderly is “the leading cause of chronic disability in developed countries.” In fact, the prevalence of OA for women between the ages of 45 and 64 is 30% and is 68% for those women older than 65. The prevalence for men is similar. (Brandt, p.1987)
OA first begins as a complicated biochemical processes in joint cartilage that eventually results in cartilage damage. Once this occurs boney spur formation can ensue. Ultimately, there is a loss of normal joint function that can lead to disability. (Cush, Kavanaugh, & Stein, p. 269.)

A common location for OA to first appear is at the base of the thumb. Unlike RA which is an inflammatory arthritis, OA tends to affect the distal interphalangeal joints of the hands. (Altman & Lozada, p.506-507.) These joints are the most distal two joints of digits two through five where digit one is the thumb.
Ultimately, when the knees or hip are affected and become severe, there may be a loss of function or avoidance of activity because of pain. This can put a patient at a risk for falls. Pain alone can also lead to a deconditioned state through avoidance of activity that worsens pain. The weakened state compounds the problem and increases the risk of falling. In turn, falls can result in further complications such as intracranial bleeding even without direct head trauma for certain at-risk elderly.

Since OA is common in the older population, what are the modifiable risk factors for developing OA? One such modifiable risk factor is obesity. While obesity increases the risk of knee OA it does not increase the risk of OA of the hip or hands. Notably, OA occurs less often in those with more bone mass. Other risk factors, which are not modifiable, include a history of “trauma…congenital or metabolic disorders…inflammatory arthritis, neuropathic arthritis, and hemophilia.” (Cush, Kavanaugh, & Stein p. 269.)

Unlike inflammatory arthritis, such as RA, noninflammatory arthritis signs and symptoms tend to initially be more subtle or of slower onset. Inflammatory arthritis also generally has associated inflammatory indicators such as redness, swelling, and/or heat that is of sudden onset at the affected joint. OA may have pain but without the signs of inflammation. Another distinguishing symptomatic characteristic of OA is that fact that pain increases with activity whereas early on in the disease progression of RA, pain is more likely to decrease with activity.

For instance, in the case of RA, the pain, stiffness, and swelling in the hand joints may be noticed on awakening in the mornings. Later in the day the pain tends to diminish with use. As activity increases during the day, the RA symptoms tend to lessen.

That said, what are the treatments for the arthritides? These are many therapeutic approaches. Some may include medical, surgical (such as joint replacement,) and joint injection therapy or any combination thereof. In the case of OA, joint injection therapy is commonly employed.

If you suffer from joint pain, over the counter agents may help. However, they may be inadequate or inappropriate depending on your specific diagnosis and other coexisting conditions. If you suffer from joint pain, see your doctor for a thorough workup, diagnosis, and treatment plan. In some cases you may be referred to a rheumatologist who is a specialist in the musculoskeletal system and many other diseases that affect multiple body systems.

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About the author: Dr. Polverino is board certified in Family Medicine. He is a practicing physician living in Colorado and does freelance writing. He has not endorsed any products.

References:

Brandt KD, Osteoarthritis. In: Braunwald E., Fauci, et. al., eds., Harrison’s Principles of
Internal Medicine, 15th ed. Chapter 32, New York: McGraw-Hill, 2001: p.1987

Cush JJ, Kavanaugh AC, and Stein, CM Rheumatology: Diagnosis
and Therapeutics 2nd ed. Philadephia: Lippincott, Williams & Wilkins, 2005: p. 269.

Altman RD and Lozada CJ, Clinical Features. In: Hochberg MC, Silman AJ, et. al., eds.,
Practical Rheumatology, 3rd ed. Chapter 39, Philadelphia: Mosby, 2004: pp. 506-507.

 

 


- What could happen to an elderly person if he or she has a fall?

Falls in the elderly in are the leading cause injury-related visits to emergency departments. Many fractures could result from a fall including, but not limited to, the hip, pelvis, and shoulder. Trauma could be caused by a fall.

The fear of falling again will could result which could be a potentially debilitating consequence. This constant fear could cause decreased socialization, decreased mobility, and a depressed mood because they lose their independence. They eventually must rely on others to take care of them.